Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase

Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase

Oxidized phospholipids stimulate endothelial cells to bind monocytes, but not neutrophils, an initiating event in atherogenesis. Here, we investigate intracellular signaling events induced by oxidized phospholipids in human umbilical vein endothelial cells (HUVECs) that lead to specific monocyte adh...

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Bibliographic Details
Main Authors: Joakim Huber, Alexander Fuärnkranz, Valery N. Bochkov, Mary K. Patricia, Hans Lee, Catherine C. Hedrick, Judith A. Berliner, Bernd R. Binder, Norbert Leitinger
Format: Article
Language:English
Published: Elsevier 2006-05-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
endothelial cells
12-lipoxygenase
cytosolic phospholipase A2
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520332545

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http://www.sciencedirect.com/science/article/pii/S0022227520332545

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