Update in the methodology of the chronic stress paradigm: internal control matters

Update in the methodology of the chronic stress paradigm: internal control matters

<p>Abstract</p> <p>To date, the reliability of induction of a depressive-like state using chronic stress models is confronted by many methodological limitations. We believe that the modifications to the stress paradigm in mice proposed herein allow some of these limitations to be o...

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Bibliographic Details
Main Authors: Boyks Marco, Kholod Natalia, Couch Yvonne, Strekalova Tatyana, Malin Dmitry, Leprince Pierre, Steinbusch Harry MW
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Behavioral and Brain Functions
Subjects:
animal model of depression
chronic stress
sucrose test
anhedonia
antidepressant treatment
gene expression profiling
neuroinflammation
mouse
Online Access:http://www.behavioralandbrainfunctions.com/content/7/1/9

Internet

http://www.behavioralandbrainfunctions.com/content/7/1/9

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