Preparation of Biodegradable Oligo(lactide)s-Grafted Dextran Nanogels for Efficient Drug Delivery by Controlling Intracellular Traffic

Preparation of Biodegradable Oligo(lactide)s-Grafted Dextran Nanogels for Efficient Drug Delivery by Controlling Intracellular Traffic

Nanogels, nanometer-sized hydrogel particles, have great potential as drug delivery carriers. To achieve effective drug delivery to the active sites in a cell, control of intracellular traffic is important. In this study, we prepared nanogels composed of dextran with oligolactide (OLA) chains attach...

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Bibliographic Details
Main Authors: Yuichi Ohya, Akihiro Takahashi, Akinori Kuzuya
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
biodegradable nanogel
disulfide bond
drug delivery
cellular traffic
Online Access:http://www.mdpi.com/1422-0067/19/6/1606

Internet

http://www.mdpi.com/1422-0067/19/6/1606

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