Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic β-cells

Pancreatic β-cells are vulnerable to oxidative stress due to their low content of redox buffers, such as glutathione, but possess a rich content of thioredoxin, peroxiredoxin, and other proteins capable of redox relay, transferring redox signaling. Consequently, it may be predicted that cytosolic an...

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Bibliographic Details
Main Authors: Lydie Plecitá-Hlavatá, Hana Engstová, Jan Ježek, Blanka Holendová, Jan Tauber, Lucie Petrásková, Vladimír Křen, Petr Ježek
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/1826303