Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine

Antiviral effects of ergosterol peroxide in a pig model of porcine deltacoronavirus (PDCoV) infection involves modulation of apoptosis and tight junction in the small intestine

Abstract Porcine deltacoronavirus (PDCoV) is a newly discovered swine enteropathogenic coronavirus with worldwide distribution. However, efficient strategies to prevent or treat the infection remain elusive. Our in vitro study revealed that ergosterol peroxide (EP) from the mushroom Cryptoporus volv...

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Bibliographic Details
Main Authors: Cong Duan, Junchi Wang, Yi Liu, Jialu Zhang, Jianyong Si, Zhihui Hao, Jiufeng Wang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Veterinary Research
Subjects:
Ergosterol peroxide
Porcine deltacoronavirus
Immunomodulatory
Antiviral
Intestinal barrier
Online Access:https://doi.org/10.1186/s13567-021-00955-5

Internet

https://doi.org/10.1186/s13567-021-00955-5

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