Changing dietary sodium alters the chronic cardiovascular effects of losartan in rats

Changing dietary sodium alters the chronic cardiovascular effects of losartan in rats

Introduction. We have previously demonstrated a profound hypotensive response to the angiotensin II type 1 (AT 1 )-receptor antagonist losartan in rats consuming a normal salt diet that is not seen in salt-loaded rats, presumably due to a suppression of the renin-angiotensin system (RAS) by high sod...

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Bibliographic Details
Main Authors:	John P Collister, David B Nahey
Format:	Article
Language:	English
Published:	Hindawi - SAGE Publishing 2008-03-01
Series:	Journal of the Renin-Angiotensin-Aldosterone System
Online Access:	https://doi.org/10.3317/jraas.2008.008

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