Changing dietary sodium alters the chronic cardiovascular effects of losartan in rats
Introduction. We have previously demonstrated a profound hypotensive response to the angiotensin II type 1 (AT 1 )-receptor antagonist losartan in rats consuming a normal salt diet that is not seen in salt-loaded rats, presumably due to a suppression of the renin-angiotensin system (RAS) by high sod...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi - SAGE Publishing
2008-03-01
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| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | https://doi.org/10.3317/jraas.2008.008 |