Exploration of Active Site-Directed Plasmin Inhibitors: Beyond Tranexamic Acid

Plasmin (Plm), a trypsin-like serine protease, is responsible for fibrinolysis pathway and pathologic events, such as angiogenesis, tumor invasion, and metastasis, and alters the expression of cytokines. A growing body of data indicates that a Plm inhibitor is a potential candidate as an anti-inflam...

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Bibliographic Details
Main Authors: Yuko Tsuda, Koushi Hidaka, Keiko Hojo, Yoshio Okada
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/9/2/329