Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile

Abstract Background In eukaryotes, heterochromatin replicates late in S phase of the cell cycle and contains specific covalent modifications of histones. SuUR mutation found in Drosophila makes heterochromatin replicate earlier than in wild type and reduces the level of repressive histone modificati...

Full description

Bibliographic Details
Main Authors: Olga V. Posukh, Daniil A. Maksimov, Petr P. Laktionov, Dmitry E. Koryakov, Stepan N. Belyakin
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-017-0163-z