The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

Abstract Background The development of essential hypertension is associated with a wide range of mechanisms. The brain stem neurons are essential for the homeostatic regulation of arterial pressure as they control baroreflex and sympathetic nerve activity. The ISIAH (Inherited Stress Induced Arteria...

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Bibliographic Details
Main Authors: Larisa A. Fedoseeva, Leonid O. Klimov, Nikita I. Ershov, Vadim M. Efimov, Arcady L. Markel, Yuriy L. Orlov, Olga E. Redina
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Genomics
Subjects:
Stress-sensitive hypertension
Brain stem
Transcriptional profiling
RNA-Seq
ISIAH rat strain
Online Access:http://link.springer.com/article/10.1186/s12864-019-5540-5

Internet

http://link.springer.com/article/10.1186/s12864-019-5540-5

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