A Novel Indoline Derivative Ameliorates Diabesity-Induced Chronic Kidney Disease by Reducing Metabolic Abnormalities

A Novel Indoline Derivative Ameliorates Diabesity-Induced Chronic Kidney Disease by Reducing Metabolic Abnormalities

Both diabetes and obesity (diabesity) contribute significantly to the development of chronic kidney disease (CKD). In search of new remedies to reverse or arrest the progression of CKD, we examined the therapeutic potential of a novel compound, AN1284, in a mouse model of CKD induced by type 2 diabe...

Full description

Bibliographic Details
Main Authors: Anna Permyakova, Asaad Gammal, Liad Hinden, Michal Weitman, Marta Weinstock, Joseph Tam
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Endocrinology
Subjects:
obesity
diabetes
chronic kidney disease
indoline derivative
insulin resistance
fatty liver
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00091/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2020.00091/full

Similar Items