Altered adenosine 2A and dopamine D2 receptor availability in the 6-hydroxydopamine-treated rats with and without levodopa-induced dyskinesia

Altered adenosine 2A and dopamine D2 receptor availability in the 6-hydroxydopamine-treated rats with and without levodopa-induced dyskinesia

Several lines of evidence imply alterations in adenosine signaling in Parkinson's disease (PD). Here, we investigated cerebral changes in adenosine 2A receptor (A2AR) availability in 6-hydroxydopamine (6-OHDA)-lesioned rats with and without levodopa-induced dyskinesia (LID) using positron-emiss...

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Bibliographic Details
Main Authors: X. Zhou, J. Doorduin, P.H. Elsinga, R.A.J.O. Dierckx, E.F.J. de Vries, C. Casteels
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:NeuroImage
Subjects:
PET
Parkinson's disease
Dopamine D2 receptor
Adenosine 2A receptor
[11C]preladenant
6-OHDA-lesioned rats
Online Access:http://www.sciencedirect.com/science/article/pii/S105381191730469X

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http://www.sciencedirect.com/science/article/pii/S105381191730469X

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