Characterization of the definitive classical calpain family of vertebrates using phylogenetic, evolutionary and expression analyses

The calpains are a superfamily of proteases with extensive relevance to human health and welfare. Vast research attention is given to the vertebrate ‘classical’ subfamily, making it surprising that the evolutionary origins, distribution and relationships of these genes is poorly characterized. Conse...

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Bibliographic Details
Main Authors: Daniel J. Macqueen, Alexander H. Wilcox
Format: Article
Language:English
Published: The Royal Society 2014-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130219