HBeAg seroconversion is associated with a more effective PD-L1 blockade during chronic hepatitis B infection

HBeAg seroconversion is associated with a more effective PD-L1 blockade during chronic hepatitis B infection

Background & Aims: Current therapies for chronic hepatitis B virus (HBV) infection control viral replication but do not eliminate the risk of progression to hepatocellular carcinoma. HBV-specific CD8 T cells are necessary for viral control, but they are rare and exhausted during chronic infectio...

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Bibliographic Details
Main Authors: Sara Ferrando-Martinez, Kelly Huang, Angie Snell Bennett, Patricia Sterba, Li Yu, JoAnn A. Suzich, Harry L.A. Janssen, Scott H. Robbins
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:JHEP Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555919300588

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http://www.sciencedirect.com/science/article/pii/S2589555919300588

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