Insulin dysfunction and Tau pathology

Insulin dysfunction and Tau pathology

The neuropathological hallmarks of Alzheimer's disease (AD) include senile plaques of β-amyloid (Aβ) peptides (a cleavage product of the Amyloid Precursor Protein, or APP) and neurofibrillary tangles (NFT) of hyperphosphorylated Tau protein assembled in paired helical filaments (PHF). NFT patho...

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Bibliographic Details
Main Authors: Noura eEl Khoury, Maud eGratuze, Marie-Amélie ePapon, Alexis eBretteville, Emmanuel ePlanel
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Diabetes Mellitus
Alzheimer’s disease
kinases
Phosphatases
Tau phosphorylation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00022/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00022/full

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