Creatine metabolism in patients with urea cycle disorders

The urea cycle generates arginine that is one of the major precursors for creatine biosynthesis. Here we evaluate levels of creatine and guanidinoacetate (the precursor in the synthesis of creatine) in plasma samples (ns = 207) of patients (np = 73) with different types of urea cycle disorders (orni...

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Bibliographic Details
Main Authors: Filippo Ingoglia, Jean-Leon Chong, Marzia Pasquali, Nicola Longo
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426921000859