Human Relaxin-2 (Serelaxin) Attenuates Oxidative Stress in Cardiac Muscle Cells Exposed In Vitro to Hypoxia–Reoxygenation. Evidence for the Involvement of Reduced Glutathione Up-Regulation

Human Relaxin-2 (Serelaxin) Attenuates Oxidative Stress in Cardiac Muscle Cells Exposed In Vitro to Hypoxia–Reoxygenation. Evidence for the Involvement of Reduced Glutathione Up-Regulation

Serelaxin (RLX) designates the pharmaceutical form of the human natural hormone relaxin-2 that has been shown to markedly reduce tissue and cell damage induced by hypoxia and reoxygenation (HR). The evidence that RLX exerts similar protective effects on different organs and cells at relatively low,...

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Bibliographic Details
Main Authors: Silvia Nistri, Claudia Fiorillo, Matteo Becatti, Daniele Bani
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
relaxin
serelaxin
cardiac muscle cells
ischemia-reperfusion
hypoxia–reoxygenation
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/9/9/774

Internet

https://www.mdpi.com/2076-3921/9/9/774

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