Low concentrations of doxycycline attenuates FasL-induced apoptosis in HeLa cells

BACKGROUND: Doxycycline (DC) has been shown to possess non-antibiotic properties including Fas/Fas Ligand (FasL)-mediated apoptosis against several tumor types in the concentration range of 10-40 μg/mL. However, the effect of DC in apoptotic signaling at much low concentrations was not studied. METH...

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Bibliographic Details
Main Authors: Jung Mi Yoon, Sushruta Koppula, Se Jong Huh, Sun Jin Hur, Chan Gil Kim
Format: Article
Language:English
Published: BMC 2015-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100038&lng=en&tlng=en