The DLC-1 tumor suppressor is involved in regulating immunomodulation of human mesenchymal stromal /stem cells through interacting with the Notch1 protein

The DLC-1 tumor suppressor is involved in regulating immunomodulation of human mesenchymal stromal /stem cells through interacting with the Notch1 protein

Abstract Background Immunomodulatory activities of human mesenchymal stromal /stem cells (hMSCs) has been widely recognized as the most critical function of hMSCs for exerting its therapeutic effects. However, the detailed mechanisms responsible for regulating the immunomodulation of hMSCs still rem...

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Bibliographic Details
Main Authors: Tao Na, Kehua Zhang, Bao-Zhu Yuan
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Cancer
Subjects:
Notch1 protein
Immunomodulation
E3 ubiqitin ligase
Deleted in liver cancer 1 (DLC-1)
Human mesenchymal stromal /stem cells (hMSCs)
Hairy/enhancer-of-split related with YRPW motif protein 1 (Hey1)
Online Access:http://link.springer.com/article/10.1186/s12885-020-07542-5

Internet

http://link.springer.com/article/10.1186/s12885-020-07542-5

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