Phylogenic inference using alignment-free methods for applications in microbial community surveys using 16s rRNA gene.

The diversity of microbiota is best explored by understanding the phylogenetic structure of the microbial communities. Traditionally, sequence alignment has been used for phylogenetic inference. However, alignment-based approaches come with significant challenges and limitations when massive amounts...

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Bibliographic Details
Main Authors: Yifei Zhang, Alexander V Alekseyenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5685621?pdf=render