High density microelectrode recording predicts span of therapeutic tissue activation volumes in subthalamic deep brain stimulation for Parkinson disease

Background: Subthalamic deep brain stimulation alleviates motor symptoms of Parkinson disease by activating precise volumes of neural tissue. While electrophysiological and anatomical correlates of clinically effective electrode sites have been described, therapeutic stimulation likely acts through...

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Bibliographic Details
Main Authors: Charles W. Lu, Karlo A. Malaga, Kelvin L. Chou, Cynthia A. Chestek, Parag G. Patil
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Brain Stimulation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X19304711