Immuno-regulatory function of indoleamine 2,3 dioxygenase through modulation of innate immune responses.

Successful long-term treatment of type-1 diabetes mainly relies on replacement of β-cells via islet transplantation. Donor shortage is one of the main obstacles preventing transplantation from becoming the treatment of choice. Although animal organs could be an alternative source for transplantation...

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Bibliographic Details
Main Authors: Malihe-Sadat Poormasjedi-Meibod, Raza B Jalili, Azadeh Hosseini-Tabatabaei, Ryan Hartwell, Aziz Ghahary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3733714?pdf=render