Disclosure of clinically actionable genetic variants to thoracic aortic dissection biobank participants

Disclosure of clinically actionable genetic variants to thoracic aortic dissection biobank participants

Abstract Background Disclosure of pathogenic variants to thoracic aortic dissection biobank participants was implemented. The impact and costs, including confirmatory genetic testing in a Clinical Laboratory Improvement Amendments (CLIA)-certified laboratory, were evaluated. Methods We exome sequenc...

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Bibliographic Details
Main Authors: Adelyn Beil, Whitney Hornsby, Wendy R. Uhlmann, Rajani Aatre, Patricia Arscott, Brooke Wolford, Kim A. Eagle, Bo Yang, Jennifer McNamara, Cristen Willer, J. Scott Roberts
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Medical Genomics
Subjects:
Biobank
Communication
Genetic counseling
Pathogenic variants
Return of results
Online Access:https://doi.org/10.1186/s12920-021-00902-5

Internet

https://doi.org/10.1186/s12920-021-00902-5

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