Projection to Latent Spaces Disentangles Pathological Effects on Brain Morphology in the Asymptomatic Phase of Alzheimer's Disease

Alzheimer's disease (AD) continuum is defined as a cascade of several neuropathological processes that can be measured using biomarkers, such as cerebrospinal fluid (CSF) levels of Aβ, p-tau, and t-tau. In parallel, brain anatomy can be characterized through imaging techniques, such as magnetic...

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Bibliographic Details
Main Authors: Adrià Casamitjana, Paula Petrone, José Luis Molinuevo, Juan Domingo Gispert, Verónica Vilaplana
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neurology
Subjects:
PLS
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00648/full