Haplopine Ameliorates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in Mice and TNF-α/IFN-γ-Induced Inflammation in Human Keratinocyte

Haplopine Ameliorates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in Mice and TNF-α/IFN-γ-Induced Inflammation in Human Keratinocyte

This study aimed to investigate the anti-inflammatory, antioxidant, and anti-atopic dermatitis (AD) effects of haplopine, which is one of the active components in <i>D. dasycarpus.</i> Haplopine (12.5 and 25 μM) inhibited the mRNA expressions of inflammatory cytokines IL-6, TSLP, GM-CSF,...

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Bibliographic Details
Main Authors: Tae-Young Kim, Ye Jin Kim, Jonghwan Jegal, Beom-Geun Jo, Han-Seok Choi, Min Hye Yang
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antioxidants
Subjects:
haplopine
atopic dermatitis
HaCaT cells
Jurkat T cells
2,4-dinitrochlorobenzene
Balb/c mice
Online Access:https://www.mdpi.com/2076-3921/10/5/806

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https://www.mdpi.com/2076-3921/10/5/806

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