Poly(ADP-ribose) polymerase 1 (PARP1) overexpression in human breast cancer stem cells and resistance to olaparib.

Poly(ADP-ribose) polymerase 1 (PARP1) overexpression in human breast cancer stem cells and resistance to olaparib.

BACKGROUND:Breast cancer stem cells (BCSCs) have been recognized as playing a major role in various aspects of breast cancer biology. To identify specific biomarkers of BCSCs, we have performed comparative proteomics of BCSC-enriched and mature cancer cell populations from the human breast cancer ce...

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Bibliographic Details
Main Authors: Marine Gilabert, Simon Launay, Christophe Ginestier, François Bertucci, Stéphane Audebert, Mathieu Pophillat, Yves Toiron, Emilie Baudelet, Pascal Finetti, Tetsuro Noguchi, Hagay Sobol, Daniel Birnbaum, Jean-Paul Borg, Emmanuelle Charafe-Jauffret, Anthony Gonçalves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4140711?pdf=render

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http://europepmc.org/articles/PMC4140711?pdf=render

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