8,9-Epoxyeicosatrienoic acid inhibits antibody production of B lymphocytes in mice.

Epoxyeicosatrienoic acids (EETs), synthesized from arachidonic acid by cytochrome P450 epoxygenases, are converted to dihydroxyeicosatrienoic acids by soluble epoxide hydrolase. EETs exert anti-inflammatory effects. However, the effect of EETs on humoral immunity is poorly understood. The present st...

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Bibliographic Details
Main Authors: Yanxiang Gao, Juan Feng, Kongyang Ma, Zhou Zhou, Yi Zhu, Qingbo Xu, Xian Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3389024?pdf=render