Effective identification of Gram-negative bacterial type III secreted effectors using position-specific residue conservation profiles.

BACKGROUND:Type III secretion systems (T3SSs) are central to the pathogenesis and specifically deliver their secreted substrates (type III secreted proteins, T3SPs) into host cells. Since T3SPs play a crucial role in pathogen-host interactions, identifying them is crucial to our understanding of the...

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Bibliographic Details
Main Authors: Xiaojiao Yang, Yanzhi Guo, Jiesi Luo, Xuemei Pu, Menglong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24391954/?tool=EBI