Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway

Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway

Background/Aims: Many clinical and experimental studies have shown that treatment with statins could prevent myocardial hypertrophy and remodeling induced by hypertension and myocardial infarction. But the molecular mechanism was not clear. We aimed to investigate the beneficial effects of atorvasta...

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Bibliographic Details
Main Authors: Yintao Chen, Ye Chang, Naijin Zhang, Xiaofan Guo, Guozhe Sun, Yingxian Sun
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Atorvastatin
Spontaneously hypertensive rats
Myocardial hypertrophy
Apoptosis
C/EBPβ
UCP3
Online Access:https://www.karger.com/Article/FullText/488832

Internet

https://www.karger.com/Article/FullText/488832

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