Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

<p>Abstract</p> <p>Background</p> <p>In this study we successfully created a new approach to ART in SIVmac251 infected nonhuman primates. This drug regimen is entirely based on drugs affecting the pre-integration stages of replication and consists of only two nucleotidi...

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Bibliographic Details
Main Authors: Greenhouse Jack, Yalley-Ogunro Jake, Chirullo Barbara, Iraci Nunzio, Collins Matt, Barreca Maria, Norelli Sandro, Lewis Mark G, Titti Fausto, Garaci Enrico, Savarino Andrea
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/7/1/21