Increased activation of Iba1+ microglia in pediatric epilepsy patients with Rasmussen's encephalitis compared with cortical dysplasia and tuberous sclerosis complex

Microgliosis is prominent in Rasmussen's encephalitis (RE), a disease with severe seizure activity. However, it is unclear if microglial activation is similar with different histopathologic substrates. Iba1-immunolabelled microglial activation was assessed in neocortex from pediatric epilepsy s...

Full description

Bibliographic Details
Main Authors: Martin Wirenfeldt, Ryan Clare, Spencer Tung, Alexander Bottini, Gary W. Mathern, Harry V. Vinters
Format: Article
Language:English
Published: Elsevier 2009-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000400