Methylmalonic acid, vitamin B12, renal function, and risk of all-cause mortality in the general population: results from the prospective Lifelines-MINUTHE study

Methylmalonic acid, vitamin B12, renal function, and risk of all-cause mortality in the general population: results from the prospective Lifelines-MINUTHE study

Abstract Background Methylmalonic acid (MMA) is best known for its use as a functional marker of vitamin B12 deficiency. However, MMA concentrations not only depend on adequate vitamin B12 status, but also relate to renal function and endogenous production of propionic acid. Hence, we aimed to inves...

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Main Authors: Ineke J. Riphagen, Isidor Minović, Dion Groothof, Adrian Post, Manfred L. Eggersdorfer, Jenny E. Kootstra-Ros, Martin H. de Borst, Gerjan Navis, Frits A. J. Muskiet, Ido P. Kema, M. Rebecca Heiner-Fokkema, Stephan J. L. Bakker
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Medicine
Online Access:https://doi.org/10.1186/s12916-020-01853-x

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