Preventive use of nitisinone in alkaptonuria

by Bruce H. R. Wolffenbuttel, M. Rebecca Heiner-Fokkema, Francjan J. van Spronsen
Published 2021-08-01

Relationship between serum B12 concentrations and mortality: experience in NHANES

by Bruce H. R. Wolffenbuttel, M. Rebecca Heiner-Fokkema, Ralph Green, Rijk O. B. Gans
Published 2020-10-01

Instability of Acylcarnitines in Stored Dried Blood Spots: The Impact on Retrospective Analysis of Biomarkers for Inborn Errors of Metabolism

by Willemijn J. van Rijt, Peter C. J. I. Schielen, Yasemin Özer, Klaas Bijsterveld, Fjodor H. van der Sluijs, Terry G. J. Derks, M. Rebecca Heiner-Fokkema
Published 2020-11-01

Aspartame and Phe-Containing Degradation Products in Soft Drinks across Europe

by Kimber van Vliet, Elise S. Melis, Pim de Blaauw, Esther van Dam, Ronald G. H. J. Maatman, David Abeln, Francjan J. van Spronsen, M. Rebecca Heiner-Fokkema
Published 2020-06-01

Inter‐laboratory analytical improvement of succinylacetone and nitisinone quantification from dried blood spot samples

by Hilde Laeremans, Charles Turner, Tommy Andersson, Jose Angel Cocho deJuan, Adam Gerrard, M. Rebecca Heiner‐Fokkema, Diran Herebian, Nils Janzen, Giancarlo laMarca, Mattias Rudebeck
Published 2020-05-01

Dried blood spot versus venous blood sampling for phenylalanine and tyrosine

by Kimber van Vliet, Wiggert G. van Ginkel, Esther van Dam, Pim de Blaauw, Martijn Koehorst, Hermi A. Kingma, Francjan J. van Spronsen, M. Rebecca Heiner-Fokkema
Published 2020-04-01

Folate reference interval estimation in the Dutch general population

by Michel J. Vos, L. Joost van Pelt, Maarten B. Kok, D.A. Janneke Dijck-Brouwer, M. Rebecca Heiner-Fokkema, Lambert D. Dikkeschei, Jenny E. Kootstra-Ros
Published 2019-08-01

Presumptive brain influx of large neutral amino acids and the effect of phenylalanine supplementation in patients with Tyrosinemia type 1.

by Willem G van Ginkel, Danique van Vliet, Johannes G M Burgerhof, Pim de Blaauw, M Estela Rubio Gozalbo, M Rebecca Heiner-Fokkema, Francjan J van Spronsen
Published 2017-01-01

The Many Faces of Cobalamin (Vitamin B12) Deficiency

by Bruce H.R. Wolffenbuttel, MD, PhD, Hanneke J.C.M. Wouters, BSc, M. Rebecca Heiner-Fokkema, PhD, Melanie M. van der Klauw, MD, PhD
Published 2019-06-01

Blood and Brain Biochemistry and Behaviour in NTBC and Dietary Treated Tyrosinemia Type 1 Mice

by Willem G. van Ginkel, Danique van Vliet, Els van der Goot, Martijn H. J. R. Faassen, Arndt Vogel, M. Rebecca Heiner-Fokkema, Eddy. A. van der Zee, Francjan J. van Spronsen
Published 2019-10-01

Biomarkers of Micronutrients in Regular Follow-Up for Tyrosinemia Type 1 and Phenylketonuria Patients

by Kimber van Vliet, Iris L. Rodenburg, Willem G. van Ginkel, Charlotte M.A. Lubout, Bruce H.R. Wolffenbuttel, Melanie M. van der Klauw, M. Rebecca Heiner-Fokkema, Francjan J. van Spronsen
Published 2019-08-01

Urinary Excretion of <i>N</i>¹-methyl-2-pyridone-5-carboxamide and <i>N</i>¹-methylnicotinamide in Renal Transplant Recipients and Donors

by Carolien P. J. Deen, Anna van der Veen, António W. Gomes-Neto, Johanna M. Geleijnse, Karin J. Borgonjen-van den Berg, M. Rebecca Heiner-Fokkema, Ido P. Kema, Stephan J. L. Bakker
Published 2020-02-01

Urinary Excretion of <i>N</i>¹-Methylnicotinamide and <i>N</i>¹-Methyl-2-Pyridone-5-Carboxamide and Mortality in Kidney Transplant Recipients

by Carolien P.J. Deen, Anna van der Veen, António W. Gomes-Neto, Johanna M. Geleijnse, Karin J. Borgonjen-van den Berg, M. Rebecca Heiner-Fokkema, Ido P. Kema, Stephan J.L. Bakker
Published 2020-07-01

Effects of magnesium citrate, magnesium oxide and magnesium sulfate supplementation on arterial stiffness in healthy overweight individuals: a study protocol for a randomized contr...

by Joëlle C. Schutten, Peter J. Joris, Ronald P. Mensink, Richard M. Danel, Frans Goorman, M. Rebecca Heiner-Fokkema, Rinse K. Weersma, Charlotte A. Keyzer, Martin H. de Borst, Stephan J. L. Bakker
Published 2019-05-01

Urinary Carnosinase-1 Excretion is Associated with Urinary Carnosine Depletion and Risk of Graft Failure in Kidney Transplant Recipients: Results of the TransplantLines Cohort Stud...

by Angelica Rodriguez-Niño, Diego O. Pastene, Adrian Post, M. Yusof Said, Antonio W. Gomes-Neto, Lyanne M. Kieneker, M. Rebecca Heiner-Fokkema, Tuba Esatbeyoglu, Gerald Rimbach, Peter Schnuelle, Benito A. Yard, Stephan J. L. Bakker
Published 2021-07-01

Methylmalonic acid, vitamin B12, renal function, and risk of all-cause mortality in the general population: results from the prospective Lifelines-MINUTHE study

by Ineke J. Riphagen, Isidor Minović, Dion Groothof, Adrian Post, Manfred L. Eggersdorfer, Jenny E. Kootstra-Ros, Martin H. de Borst, Gerjan Navis, Frits A. J. Muskiet, Ido P. Kema, M. Rebecca Heiner-Fokkema, Stephan J. L. Bakker
Published 2020-12-01

Large Neutral Amino Acid Supplementation Exerts Its Effect through Three Synergistic Mechanisms: Proof of Principle in Phenylketonuria Mice.

by Danique van Vliet, Vibeke M Bruinenberg, Priscila N Mazzola, Martijn H J R van Faassen, Pim de Blaauw, Ido P Kema, M Rebecca Heiner-Fokkema, Rogier D van Anholt, Eddy A van der Zee, Francjan J van Spronsen
Published 2015-01-01

The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine-Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult <i>Pah-Enu2</i> Mice

by Danique van Vliet, Els van der Goot, Wiggert G. van Ginkel, Martijn H. J. R. van Faassen, Pim de Blaauw, Ido P. Kema, Aurora Martinez, M. Rebecca Heiner-Fokkema, Eddy A. van der Zee, Francjan J. van Spronsen
Published 2019-09-01

A toolbox for the comprehensive analysis of small volume human intestinal samples that can be used with gastrointestinal sampling capsules

by Melany Rios-Morales, Mara P. H. van Trijp, Christiane Rösch, Ran An, Theo Boer, Albert Gerding, Naomi de Ruiter, Martijn Koehorst, M. Rebecca Heiner-Fokkema, Henk A. Schols, Dirk-Jan Reijngoud, Guido J. E. J. Hooiveld, Barbara M. Bakker
Published 2021-04-01

The Effect of Various Doses of Phenylalanine Supplementation on Blood Phenylalanine and Tyrosine Concentrations in Tyrosinemia Type 1 Patients

by Willem G. van Ginkel, Hannah E. van Reemst, Nienke S. Kienstra, Anne Daly, Iris L. Rodenburg, Anita MacDonald, Johannes G.M. Burgerhof, Pim de Blaauw, Jennifer van de Krogt, Saikat Santra, M. Rebecca Heiner-Fokkema, Francjan J. van Spronsen
Published 2019-11-01