Pd(PPh<sub>3</sub>)<sub>4 </sub>Catalyzed Synthesis of Indazole Derivatives as Potent Anticancer Drug

Pd(PPh<sub>3</sub>)<sub>4 </sub>Catalyzed Synthesis of Indazole Derivatives as Potent Anticancer Drug

A series of 3-aryl indazoles and 1-methyl-3-aryl indazole derivatives are prepared with exceptional yields by coupling with several arylboronic acids and methylation by two dissimilar approaches. The as-prepared indazole derivatives (<b>3a-3j</b>) and their N-methyl derivatives (<b>...

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Bibliographic Details
Main Authors: Jagan Mohana Rao Saketi, S. N. Murthy Boddapati, Raghuram M., Syed Farooq Adil, Mohammed Rafi Shaik, Osamah Alduhaish, Mohammed Rafiq H. Siddiqui, Hari Babu Bollikolla
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Applied Sciences
Subjects:
Pd(PPh<sub>3</sub>)<sub>4</sub>
indazole
anticancer activity
HCT-116
MDA-MB-231
Online Access:https://www.mdpi.com/2076-3417/10/11/3792

Internet

https://www.mdpi.com/2076-3417/10/11/3792

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