Highly improved homopolymer aware nucleotide-protein alignments with 454 data

<p>Abstract</p> <p>Background</p> <p>Roche 454 sequencing is the leading sequencing technology for producing long read high throughput sequence data. Unlike most methods where sequencing errors translate to base uncertainties, 454 sequencing inaccuracies create nucleoti...

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Bibliographic Details
Main Author: Lysholm Fredrik
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/230