TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell

Transcription factor 19 (TCF19) is a gene associated with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in genome-wide association studies. Prior studies have demonstrated that Tcf19 knockdown impairs β-cell proliferation and increases apoptosis. However, little is known about its role in diabet...

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Bibliographic Details
Main Authors: Grace H. Yang, Danielle A. Fontaine, Sukanya Lodh, Joseph T. Blumer, Avtar Roopra, Dawn Belt Davis
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/8/513