Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei

Summary: Extended synaptotagmins (E-Syts) localize at membrane contact sites between the endoplasmic reticulum (ER) and the plasma membrane to mediate inter-membrane lipid transfer and control plasma membrane lipid homeostasis. All known E-Syts contain an N-terminal transmembrane (TM) hairpin, a cen...

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Bibliographic Details
Main Authors: Emma Stepinac, Nicolas Landrein, Daria Skwarzyńska, Patrycja Wójcik, Johannes Lesigang, Iva Lučić, Cynthia Y. He, Mélanie Bonhivers, Derrick R. Robinson, Gang Dong
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221003904