Development of a preclinical orthotopic xenograft model of ewing sarcoma and other human malignant bone disease using advanced in vivo imaging.

Development of a preclinical orthotopic xenograft model of ewing sarcoma and other human malignant bone disease using advanced in vivo imaging.

Ewing sarcoma and osteosarcoma represent the two most common primary bone tumours in childhood and adolescence, with bone metastases being the most adverse prognostic factor. In prostate cancer, osseous metastasis poses a major clinical challenge. We developed a preclinical orthotopic model of Ewing...

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Bibliographic Details
Main Authors: Britta Vormoor, Henrike K Knizia, Michael A Batey, Gilberto S Almeida, Ian Wilson, Petra Dildey, Abhishek Sharma, Helen Blair, I Geoff Hide, Olaf Heidenreich, Josef Vormoor, Ross J Maxwell, Chris M Bacon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3883696?pdf=render

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http://europepmc.org/articles/PMC3883696?pdf=render

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