DHZCP Modulates Microglial M1/M2 Polarization via the p38 and TLR4/NF-κB Signaling Pathways in LPS-Stimulated Microglial Cells

DHZCP Modulates Microglial M1/M2 Polarization via the p38 and TLR4/NF-κB Signaling Pathways in LPS-Stimulated Microglial Cells

Intracerebral hemorrhage (ICH) is a disease with a significantly high rate of morbidity, mortality and disability. Inhibition of inflammation is considered a potential strategy for improving the clinical symptoms induced by ICH. The hallmark of neuroinflammation is microglial activation. Microglia c...

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Bibliographic Details
Main Authors: Lu Zhou, Dongsheng Wang, Xinjian Qiu, Weiru Zhang, Zhicheng Gong, Yang Wang, Xia Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
Dahuang Zhechong Pill (DHZCP)
antiinflammatory effects
microglia polarization
p38
TLR4/NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01126/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01126/full

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