In silico transcriptional analysis of mRNA and miRNA reveals unique biosignatures that characterizes different types of diabetes.

Diabetes (DM) has a significant impact on public health. We performed an in silico study of paired datasets of messenger RNA (mRNA) micro-RNA (miRNA) transcripts to delineate potential biosignatures that could distinguish prediabetes (pre-DM), type-1DM (T1DM) and type-2DM (T2DM). Two publicly availa...

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Bibliographic Details
Main Authors: Juan M Cubillos-Angulo, Caian L Vinhaes, Eduardo R Fukutani, Victor V S Albuquerque, Artur T L Queiroz, Bruno B Andrade, Kiyoshi F Fukutani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0239061