Decreased Expression of the Polarity Regulatory PAR Complex Predicts Poor Prognosis of the Patients with Colorectal Adenocarcinoma
Partitioning defective (Par) proteins regulate cell polarity and differentiation. Par3, Par6β, and protein kinase Cζ (PKCζ), which are PAR complex members, have been shown to be associated with oncogenesis and progression. Herein, we report the expression pattern and clinical relevance of Par3, Par6...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-02-01
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Series: | Translational Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S193652331730373X |