Decreased Expression of the Polarity Regulatory PAR Complex Predicts Poor Prognosis of the Patients with Colorectal Adenocarcinoma

Partitioning defective (Par) proteins regulate cell polarity and differentiation. Par3, Par6β, and protein kinase Cζ (PKCζ), which are PAR complex members, have been shown to be associated with oncogenesis and progression. Herein, we report the expression pattern and clinical relevance of Par3, Par6...

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Bibliographic Details
Main Authors: Min-Kyung Yeo, Jin-Man Kim, Kwang-Sun Suh, Seok-Hyung Kim, Ok-Jun Lee, Kyung-Hee Kim
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652331730373X