The Link Between Tau and Insulin Signaling: Implications for Alzheimer’s Disease and Other Tauopathies

The microtubule-associated protein tau (MAPT) is mainly identified as a tubulin binding protein essential for microtubule dynamics and assembly and for neurite outgrowth. However, several other possible functions for Tau remains to be investigated. Insulin signaling is important for synaptic plastic...

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Bibliographic Details
Main Authors: Rafaella Araujo Gonçalves, Nadeeja Wijesekara, Paul E. Fraser, Fernanda G. De Felice
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00017/full