c-Jun N-terminal kinase 3 expression in the retina of ocular hypertension mice: a possible target to reduce ganglion cell apoptosis

Glaucoma, a type of optic neuropathy, is characterized by the loss of retinal ganglion cells. It remains controversial whether c-Jun N-terminal kinase (JNK) participates in the apoptosis of retinal ganglion cells in glaucoma. This study sought to explore a possible mechanism of action of JNK signali...

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Bibliographic Details
Main Authors:	Yue He, Jie Chen, Shu-guang Zhang, Yuan-sheng Yuan, Yan Li, Hong-bin Lv, Jin-hua Gan
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2015-01-01
Series:	Neural Regeneration Research
Subjects:	tamoxifen Src kinase PP2 trauma regeneration neuroprotection auranofin dextromethorphan rosiglitazone Alzheimer′s disease neuroinflammation neurodegeneration microglia astrocytes nerve regeneration spinal cord electroacupuncture therapy neural stem cells notch signaling pathway inflammation survival curve proliferation differentiation real-time quantitative PCR western blot assay neural regeneration superparamagnetic iron oxide magnetic guidance bone marrow mesenchymal stem cells spinal cord injury cell transplantation magnetic resonance image lumbar puncture spinal cord transection average combined score magnetic resonance imaging diffusion tensor imaging fractional anisotropy apparent diffusion coefficient fiber tractography peripheral nerve injury sciatic nerve hypothermia blood-nerve barrier Evans blue tracer neural degeneration polyethyleneimine-polyethylene glycol spiral ganglion cells X-linked inhibitor of apoptosis protein gene therapy nanocarrier cisplatin ototoxicity cochlea ocular hypertension JNK3 retinal ganglion cell glaucoma laser photocoagulation intraocular pressure
Online Access:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=3;spage=432;epage=437;aulast=He

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=3;spage=432;epage=437;aulast=He

c-Jun N-terminal kinase 3 expression in the retina of ocular hypertension mice: a possible target to reduce ganglion cell apoptosis

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