Structure, Dynamics, and Ligand Recognition of Human-Specific CHRFAM7A (Dupα7) Nicotinic Receptor Linked to Neuropsychiatric Disorders
Cholinergic α7 nicotinic receptors encoded by the <i>CHRNA7</i> gene are ligand-gated ion channels directly related to memory and immunomodulation. Exons 5–7 in <i>CHRNA7</i> can be duplicated and fused to exons A-E of <i>FAR7a</i>, resulting in a hybrid gene know...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/11/5466 |