Post-Translational Modifications of FXR; Implications for Cholestasis and Obesity-Related Disorders

The Farnesoid X receptor (FXR) is a nuclear receptor which is activated by bile acids. Bile acids function in solubilization of dietary fats and vitamins in the intestine. In addition, bile acids have been increasingly recognized to act as signaling molecules involved in energy metabolism pathways,...

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Bibliographic Details
Main Authors: Monique D. Appelman, Suzanne W. van der Veen, Saskia W. C. van Mil
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.729828/full