BCAT1 Activates PI3K/AKT/mTOR Pathway and Contributes to the Angiogenesis and Tumorigenicity of Gastric Cancer

BCAT1 Activates PI3K/AKT/mTOR Pathway and Contributes to the Angiogenesis and Tumorigenicity of Gastric Cancer

BackgroundFocusing on antiangiogenesis may provide promising choices for treatment of gastric cancer (GC). This study aimed to investigate the mechanistic role of BCAT1 in the pathogenesis of GC, particularly in angiogenesis.MethodsBioinformatics and clinical samples analysis were used to investigat...

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Bibliographic Details
Main Authors: Xiong Shu, Pan-Pan Zhan, Li-Xin Sun, Long Yu, Jun Liu, Li-Chao Sun, Zhi-Hua Yang, Yu-Liang Ran, Yue-Min Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
branched-chain aminotransferases
BCAT1
angiopoiesis
tumorigenicity
oncogene
gastric cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.659260/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.659260/full

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