Identification of a Preneoplastic Gene Expression Profile in Tubal Epithelium of BRCA1 Mutation Carriers

Microinvasive carcinomas and high-grade intraepithelial neoplasms are commonly discovered within the fallopian tube of BRCA1 mutation carriers at the time of risk-reducing salpingo-oophorectomy, suggesting that many BRCA1-mutated ovarian carcinomas originate in tubal epithelium. We hypothesized tha...

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Bibliographic Details
Main Authors: Joshua Z. Press, Kaitlyn Wurz, Barbara M. Norquist, Ming K. Lee, Christopher Pennil, Rochelle Garcia, Piri Welcsh, Barbara A. Goff, Elizabeth M. Swisher
Format: Article
Language:English
Published: Elsevier 2010-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861080017X