The critical role of piperamide derivative D4 in the regulation of inflammatory response by the microglia and astrocytic glial cells

Acute and chronic inflammation in the central nervous system plays a critical role in the development of neurodegenerative disorders. Various pro-inflammatory cytokines, chemokines, and enzymes such as TNF-α, IL1-β, IL-6, COX-1, COX-2, iNOS, IKK, and inducible nitric oxide are expressed in several s...

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Bibliographic Details
Main Authors: Sajad Shahbazi, Tara Zakerali, Bartosz A. Frycz, Jagdeep Kaur
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220310878