Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI.

RsmI and RsmH are conserved S-Adenosylmethionine (AdoMet)-dependent methyltransferases (MTases) that are responsible for the 2'-O-methylation and N4-methylation of C1402 in bacterial 16S rRNA, respectively. Methylation of m4Cm1402 plays a role in fine-tuning the shape and functions of the P-sit...

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Bibliographic Details
Main Authors: Mohan Zhao, Heng Zhang, Guangfeng Liu, Li Wang, Jian Wang, Zengqiang Gao, Yuhui Dong, Linbo Zhang, Yong Gong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5053481?pdf=render