An improved random forest-based computational model for predicting novel miRNA-disease associations

Abstract Background A large body of evidence shows that miRNA regulates the expression of its target genes at post-transcriptional level and the dysregulation of miRNA is related to many complex human diseases. Accurately discovering disease-related miRNAs is conductive to the exploring of the patho...

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Bibliographic Details
Main Authors: Dengju Yao, Xiaojuan Zhan, Chee-Keong Kwoh
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3290-7